Exercise has an impact on DNA, according to a study from the University of Copenhagen, Dublin City University, and Sweden’s Karolinska Institute. The Cell Metabolism journal published this study. In the study, 14 men and women were asked to exercise on a stationary bike until they were exhausted.
Two groups working out at different intervals examined
The participants’ muscles were sampled before the workout and again 20 minutes later. Following a comparison of the genes of the study’s human participants, some biochemical processes were noticed.
A small set of 8 men completed two additional workouts, one session at low intensity at 40% of their maximum reaction and another group at a high level at 80%. Before, shortly after, and three hours after the workout, muscle samples were taken. Additionally, 48 hours following a three-week workout program, muscle samples were examined.
This study found that exercise reduces the DNA’s methylation, which is a chemical process. Note that there is no alteration to the DNA coding itself.
DNA is attached to methyl, a molecule made up of one carbon atom and two hydrogen atoms, during the biochemical DNA methylation process.
Methylation aids in getting the muscle cells ready for a workout. It promotes the release of nutrients and enzymes that the muscle needs to use up energy and burn more calories. The methyl element on the DNA is depleted with increased activity.
Exercises cause temporary DNA methylation
Be aware that several protein components that control gene expression cannot bind to DNA because of the existence of methyl. As a result, the muscle cell’s reduced methyl groups allow the protein components to reach the DNA. The muscle cell may be prompted to import specialized protein as a result, which may encourage growth and boost muscle capacity.
Researchers discovered that high-intensity activity significantly reduced DNA methylation relative to low exercise when they analyzed the small group of subjects who completed the low and high-intensity sessions. Further investigation discovered that the impact is temporary.
Another study has shown that caffeine can cause DNA methylation reduction and boost genetic activity.