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The emergence of “Ozempic babies” stories involves women experiencing unexpected pregnancies while using drugs like Ozempic (semaglutide). Questions arise regarding semaglutide’s impact on fertility, particularly its potential to enhance it under its other name, Wegovy.

Obesity affects fertility and menstrual cycle

Ozempic, a GLP-1 receptor agonist, is designed to manage blood sugar levels in type 2 diabetes. Its global popularity stems from its dual benefit of aiding weight loss through slowing stomach emptying and curbing appetite. This drug, prescribed in Australia for diabetes, is sometimes used off-label for weight loss. Although it is approved for obesity in Australia it is not yet accessible.

Obesity disrupts hormonal balance, impacting the menstrual cycle and fertility. Women with a BMI over 27 are three times more likely to struggle with ovulation. Conditions like polycystic ovary syndrome (PCOS) and type II Diabetes, often associated with obesity, further complicate fertility. Type 2 diabetes increases the risk of obesity and fertility issues, including miscarriage. PCOS leads to irregular menstrual cycles and difficulty conceiving, exacerbated by obesity. In men, obesity, diabetes, and metabolic syndrome decrease fertility, affecting sperm quality due to low testosterone levels.

Ozempic increases chances of pregnancy in women

Ozempic may impact fertility through weight loss and metabolic improvements, potentially increasing the likelihood of pregnancy in women with obesity. Reports suggest unexpected pregnancies among women using Ozempic, even when also using contraceptive pills, prompting speculation about possible interactions affecting pill absorption. However, the exact connection between Ozempic and contraceptive failure remains uncertain. In men with type 2 diabetes, obesity, and low testosterone, Ozempic and similar drugs show promise in weight loss and boosting testosterone levels.

To prevent potential risks to fetal health, it’s advised to avoid Ozempic if you’re planning to conceive. Animal studies indicate possible fetal abnormalities, so the Therapeutic Goods Administration suggests using contraception while on semaglutide.

Women with PCOS using Ozempic should also ensure effective contraception as per guidelines. It’s recommended to stop semaglutide at least two months before attempting pregnancy.

For women using Ozempic for diabetes management, it’s crucial to explore alternative methods for regulating blood sugar during pregnancy attempts.