Researchers have discovered the rejuvenating potential of young blood as an anti-aging treatment, akin the concept of vampires sucking young blood.
Young blood could offer anti-aging properties
Duke University researchers found that linking the circulatory systems of young and old mice can slow cellular aging and increase the older mouse’s lifespan by around 10%. The study at Duke Health also revealed that the duration of the anti-aging benefits increased with longer periods of combined circulatory systems.
The research suggests that young people may have unique blood components linked to vitality. If these elements can be pinpointed, it may open doors for therapies to speed up healing, invigorate the body, and potentially extend lifespan.
This marks the initial confirmation that the technique, known as heterochronic parabiosis, has the potential to decelerate the aging process, resulting in an increase in both lifespan and overall health. Dr. James White, the lead author of the study and an assistant professor in the Departments of Medicine and Cell Biology at Duke University School of Medicine, as well as the Duke Aging Center, asserts this groundbreaking finding.
Heterochronic parabiosis is a procedure wherein two animals of varying ages are surgically combined to jointly circulate their blood. The main objective was to investigate whether the advantages of this procedure had a transient nature or a longer-lasting impact.
Researchers demonstrated anti-aging following heterochronic parabiosis
Prior investigations conducted by Duke University and other research organizations documented anti-aging effects in older mice following three weeks of shared circulation with younger mice. These mature mice manifested heightened activity levels, and their bodily tissues displayed indications of revitalization.
In the study using both young mice (four months old) and older mice (two years old), the older mice experienced improved physiological functions and a 10% increase in lifespan compared to their counterparts who did not undergo the procedure. This effect persisted even two months after the separation. The process also reduced the epigenetic age of blood and liver tissue in the older mice and led to gene expression changes that combat aging, similar to the benefits observed with methods like calorie restriction.